Pub. Date : 2004 Aug 1
PMID : 15297391
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PURPOSE: The oral fluoropyrimidine S-1, which consists of a mixture of a 5-fluorouracil (5-FU) prodrug (tegafur), a dihydropyrimidine dehydrogenase inhibitor [5-chloro-2,4-dihydroxypyrimidine (CDHP)], and an inhibitor of orotate phosphoribosyltransferase [potassium oxonate (oxonic acid)], was developed to increase the feasibility and therapeutic index of 5-FU administered orally. | Tegafur | proteasome 26S subunit, non-ATPase 1 | Homo sapiens |