Title : Gene-selective modulation by a synthetic oxysterol ligand of the liver X receptor.

Pub. Date : 2004 Oct

PMID : 15292374






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 A newly characterized synthetic oxysterol, N,N-dimethyl-3beta-hydroxycholenamide (DMHCA), represents a gene-selective LXR modulator that mediates potent transcriptional activation of ABCA1 gene expression while exhibiting minimal effects on SREBP-1c both in vitro and in vivo in mice. Oxysterols nuclear receptor subfamily 1, group H, member 3 Mus musculus