Title : Polymorphism of estrogen metabolism genes and cataract.

Pub. Date : 2004

PMID : 15288375






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Polymorphism such as cytochrome P450c17 (A2/A2), cytochrome P450c1A (vt/vt) will result in increased formation of catechol estrogen, while people with catechol-O-methyltransferase (COMT) polymorphism COMT (L/L) will have decreased metabolism of catechol estrogen and decreased level of methoxyestradiol. Methoxyestradiol cytochrome P450 family 17 subfamily A member 1 Homo sapiens