Pub. Date : 2004 Aug 15
PMID : 15264228
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | M239V-PS2 exerted three forms of cytotoxicity: one was sensitive to both an antioxidant glutathione-ethyl-ester (GEE) and a caspase inhibitor Ac-DEVD-CHO (DEVD); the second was sensitive to GEE but resistant to DEVD; and the third was resistant to both. | DEVD | presenilin 2 | Homo sapiens |
| 2 | M239V-PS2 exerted three forms of cytotoxicity: one was sensitive to both an antioxidant glutathione-ethyl-ester (GEE) and a caspase inhibitor Ac-DEVD-CHO (DEVD); the second was sensitive to GEE but resistant to DEVD; and the third was resistant to both. | DEVD | presenilin 2 | Homo sapiens |
| 3 | The GEE/DEVD-sensitive cytotoxicity by M239V-PS2 was likely through NADPH oxidase and the GEE-sensitive/DEVD-resistant cytotoxicity through xanthine oxidase (XO). | DEVD | presenilin 2 | Homo sapiens |