Pub. Date : 2004 Sep
PMID : 15262904
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Reduction of vascular noradrenaline sensitivity by AT1 antagonists depends on functional sympathetic innervation. | Norepinephrine | angiotensin II receptor, type 1a | Rattus norvegicus |
2 | Blockade of angiotensin II type-1 (AT1) receptors has been shown to reduce the magnitude of the blood pressure response to noradrenaline in pithed rats via an unidentified mechanism. | Norepinephrine | angiotensin II receptor, type 1a | Rattus norvegicus |
3 | Our experiments show that the reduction of vascular noradrenaline sensitivity by AT1 blockade is dependent on the intact functioning of both neuronal noradrenaline uptake via norepinephrine transporter and presynaptic alpha2-mediated autoinhibition, exclusively provided by the sympathetic innervation. | Norepinephrine | angiotensin II receptor, type 1a | Rattus norvegicus |
4 | Our experiments show that the reduction of vascular noradrenaline sensitivity by AT1 blockade is dependent on the intact functioning of both neuronal noradrenaline uptake via norepinephrine transporter and presynaptic alpha2-mediated autoinhibition, exclusively provided by the sympathetic innervation. | Norepinephrine | angiotensin II receptor, type 1a | Rattus norvegicus |