Title : Effects of polyunsaturated fatty acids on prostaglandin synthesis and cyclooxygenase-mediated DNA adduct formation by heterocyclic aromatic amines in human adenocarcinoma colon cells.

Pub. Date : 2004 Jul

PMID : 15224350






1 Functional Relationships(s)
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1 Both IM and NS-398 inhibited adduct formation by HCA to nearly the same extent, indicating involvement of COX-2 rather than COX-1, while CYP1A2 activity in HCA-7 cells was demonstrated by addition of PEITC. phenethyl isothiocyanate cytochrome P450 family 1 subfamily A member 2 Homo sapiens