Title : Positive feedback regulation of PLCgamma1/Ca(2+) signaling by PKCtheta in restimulated T cells via a Tec kinase-dependent pathway.

Pub. Date : 2004 Jul

PMID : 15214048






1 Functional Relationships(s)
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1 Here, we report that the TCR/CD28-induced tyrosine phosphorylation and activation of PLCgamma1 was significantly impaired in PKCtheta (-/-) primary, restimulated T cells. Tyrosine phospholipase C gamma 1 Homo sapiens