Title : Histamine inhibits lipopolysaccharide-induced interleukin (IL)-18 production in human monocytes.

Pub. Date : 2004 Jul

PMID : 15207779






2 Functional Relationships(s)
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1 Histamine inhibits lipopolysaccharide-induced interleukin (IL)-18 production in human monocytes. Histamine interleukin 18 Homo sapiens
2 In the present study, we found that LPS at relatively high concentrations (10-1000 ng/ml) induced IL-18 production in a concentration-dependent manner both in monocytes isolated from PBMC, and that histamine (10(-7) to 10(-4) M) inhibited IL-18 production induced by LPS. Histamine interleukin 18 Homo sapiens