Pub. Date : 2004 Oct
PMID : 15198932
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Recently, the farnesoid X receptor (FXR), constitutive androstane receptor (CAR), and pregnane X receptor (PXR) were found to regulate DHEA sulfotransferase (Sult2A1), which plays an important role in DHEA sulfation and detoxification of bile acids. | Dehydroepiandrosterone | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
| 2 | Recently, the farnesoid X receptor (FXR), constitutive androstane receptor (CAR), and pregnane X receptor (PXR) were found to regulate DHEA sulfotransferase (Sult2A1), which plays an important role in DHEA sulfation and detoxification of bile acids. | Dehydroepiandrosterone | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
| 3 | These results suggest that decreased levels or activities of FXR, PXR, and CAR during the APR could contribute to decreases in Sult2A1, resulting in decreased sulfation of DHEA and lower circulating level of DHEA-S. | Dehydroepiandrosterone | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
| 4 | These results suggest that decreased levels or activities of FXR, PXR, and CAR during the APR could contribute to decreases in Sult2A1, resulting in decreased sulfation of DHEA and lower circulating level of DHEA-S. | Dehydroepiandrosterone | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |