Pub. Date : 2004 Jun 28
PMID : 15194873
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Corticosterone strongly increases the affinity of dorsal raphe 5-HT1A receptors. | Corticosterone | 5-hydroxytryptamine receptor 1A | Rattus norvegicus |
| 2 | Corticosterone increases 5-HT1A autoreceptor agonist affinity (+90%, p<0.001) in adrenalectomized rats. | Corticosterone | 5-hydroxytryptamine receptor 1A | Rattus norvegicus |
| 3 | Dorsal raphe glucocorticoid receptors activation by corticosterone may therefore lead to an increased signalling of 5-HT1A autoreceptors that may become counteracted by galanin receptor activation. | Corticosterone | 5-hydroxytryptamine receptor 1A | Rattus norvegicus |