Title : Targeting of epidermal growth factor receptor by cyclopentenone prostaglandin 15-Deoxy-Delta12,14-prostaglandin J2 in human oral squamous carcinoma cells.

Pub. Date : 2004 Jul 28

PMID : 15194221






2 Functional Relationships(s)
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1 Targeting of epidermal growth factor receptor by cyclopentenone prostaglandin 15-Deoxy-Delta12,14-prostaglandin J2 in human oral squamous carcinoma cells. cyclopentenone epidermal growth factor receptor Homo sapiens
2 These findings provide evidence for EGFR downregulation in oral SCC cells through a novel anticancer effect of 15d-PGJ2 that is attributed to the reactive cyclopentenone ring system. cyclopentenone epidermal growth factor receptor Homo sapiens