Title : Novel mechanism of action for hydralazine: induction of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by inhibition of prolyl hydroxylases.

Pub. Date : 2004 Jul 23

PMID : 15192023






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Hydralazine induced rapid and transient expression of HIF-1alpha and downstream targets of HIF (endothelin-1, adrenomedullin, haem oxygenase 1, and vascular endothelial growth factor [VEGF]) in endothelial and smooth muscle cells and induced endothelial cell-specific proliferation. Hydralazine endothelin 1 Homo sapiens