Title : Involvement of cytochrome P450 1A in sanguinarine detoxication.

Pub. Date : 2004 Jul 15

PMID : 15183462






1 Functional Relationships(s)
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1 Using microsomes containing recombinant CYP1A1 or CYP1A2 we show that SA causes non-competitive inhibition of the former and competitive inhibition of the latter as assessed by ethoxyresorufin de-ethylation (EROD). sanguinarine cytochrome P450 family 1 subfamily A member 1 Homo sapiens