Pub. Date : 2004 Sep 1
PMID : 15171728
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PDI (protein disulphide-isomerase) has recently been found to be localized to the cell surface, where it exhibits both disulphide-exchange and denitrosation activities. | disulphide | prolyl 4-hydroxylase subunit beta | Homo sapiens |
| 2 | The disulphide-exchange activity of PDI has been linked to aspects of platelet aggregation. | disulphide | prolyl 4-hydroxylase subunit beta | Homo sapiens |
| 3 | Secondly, RSNOs are denitrosated at the same PDI-active site that catalyses the disulphide bond formation between integrins and their ligands, thereby attenuating irreversible aggregation. | disulphide | prolyl 4-hydroxylase subunit beta | Homo sapiens |