Pub. Date : 2004 Jun
PMID : 15167270
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 5-HT-induced contraction of normal aorta was potentiated by the 5-HTT inhibitor fluvoxamine. | Fluvoxamine | solute carrier family 6 member 4 | Rattus norvegicus |
| 2 | A change in arterial 5-HTT function occurs in deoxycorticosterone (DOCA)-salt hypertension as the potency and threshold of 5-HT in contracting aorta from the DOCA-salt rat was increased by fluoxetine and fluvoxamine (1 micromol/L; DOCA fluvoxamine -log EC50 [mol/L] = 6.85 +/- 0.08, DOCA-control = 6.44 +/- 0.08); expression of transporter was significantly increased in aorta of DOCA salt rats (145% Sham). | Fluvoxamine | solute carrier family 6 member 4 | Rattus norvegicus |