Pub. Date : 2004 May 27
PMID : 15158023
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The KCNQ channel activator retigabine blocks haloperidol-induced c-Fos expression in the striatum of the rat. | Haloperidol | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 2 | Haloperidol produced a large increase in the number of c-Fos-positive nuclei in different degrees in all parts of the striatum. | Haloperidol | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 3 | Pretreatment with retigabine completely blocked haloperidol-induced c-Fos in both the ventral and dorsal striatum suggesting that retigabine via activation of the KCNQ channel interacts with haloperidol and inhibits neuronal excitation in the striatum. | Haloperidol | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 4 | Pretreatment with retigabine completely blocked haloperidol-induced c-Fos in both the ventral and dorsal striatum suggesting that retigabine via activation of the KCNQ channel interacts with haloperidol and inhibits neuronal excitation in the striatum. | Haloperidol | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |