Title : Phosphatase 2A is involved in endothelial cell microtubule remodeling and barrier regulation.

Pub. Date : 2004 Jun 1

PMID : 15156565






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Okadaic acid (OA, 2-5 nM), a powerful inhibitor of protein phosphatase 2A (PP2A), significantly potentiates the effect of submaximal concentrations of nocodazole (50-200 nM) on transendothelial electrical resistance (TER) suggesting the involvement of PP2A activity in the MT-mediated EC barrier regulation. Nocodazole protein phosphatase 2 phosphatase activator Homo sapiens
2 Okadaic acid (OA, 2-5 nM), a powerful inhibitor of protein phosphatase 2A (PP2A), significantly potentiates the effect of submaximal concentrations of nocodazole (50-200 nM) on transendothelial electrical resistance (TER) suggesting the involvement of PP2A activity in the MT-mediated EC barrier regulation. Nocodazole protein phosphatase 2 phosphatase activator Homo sapiens
3 Okadaic acid (OA, 2-5 nM), a powerful inhibitor of protein phosphatase 2A (PP2A), significantly potentiates the effect of submaximal concentrations of nocodazole (50-200 nM) on transendothelial electrical resistance (TER) suggesting the involvement of PP2A activity in the MT-mediated EC barrier regulation. Nocodazole protein phosphatase 2 phosphatase activator Homo sapiens