Title : Extrasynaptic NR2B and NR2D subunits of NMDA receptors shape 'superslow' afterburst EPSC in rat hippocampus.

Pub. Date : 2004 Jul 15

PMID : 15146049






1 Functional Relationships(s)
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1 The competitive NMDA antagonist R-(-)-3-(2-carboxypiperazine-4-yl)-propyl-1-phosphonic acid (D-CPP), which has higher affinity to NR2A than to NR2B subunits and lowest affinity at NR2D subunits, significantly slowed down the decay rate of the afterburst EPSC while leaving the kinetics of the control current unaffected. N-Methylaspartate glutamate ionotropic receptor NMDA type subunit 2A Rattus norvegicus