Pub. Date : 2004 Apr
PMID : 15139520
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | D-glucose triggers multidrug resistance-associated protein (MRP)-mediated secretion of fluorescein across rat jejunum in vitro. | Fluorescein | ATP binding cassette subfamily C member 2 | Rattus norvegicus |
| 2 | D-glucose triggers multidrug resistance-associated protein (MRP)-mediated secretion of fluorescein across rat jejunum in vitro. | Fluorescein | ATP binding cassette subfamily C member 2 | Rattus norvegicus |
| 3 | PURPOSE: To examine the transport characteristics of the multidrug resistance-associated protein (MRP) substrate fluorescein across the isolated rat small intestinal segments. | Fluorescein | ATP binding cassette subfamily C member 2 | Rattus norvegicus |
| 4 | PURPOSE: To examine the transport characteristics of the multidrug resistance-associated protein (MRP) substrate fluorescein across the isolated rat small intestinal segments. | Fluorescein | ATP binding cassette subfamily C member 2 | Rattus norvegicus |
| 5 | The polarization of fluorescein transport was almost completely abolished by MRP inhibitor, benzbromarone (50 or 100 microM, applied apically), and by MRP/P-glycoprotein inhibitor, verapamil (200 microM, applied apically). | Fluorescein | ATP binding cassette subfamily C member 2 | Rattus norvegicus |
| 6 | The polarization of fluorescein transport was almost completely abolished by MRP inhibitor, benzbromarone (50 or 100 microM, applied apically), and by MRP/P-glycoprotein inhibitor, verapamil (200 microM, applied apically). | Fluorescein | ATP binding cassette subfamily C member 2 | Rattus norvegicus |
| 7 | CONCLUSIONS: D-glucose at the mucosal side activates fluorescein secretion across rat jejunum by an apical MRP, most probably by isoform 2 (MRP2), which could have an impact on the intestinal absorption of MRP substrates. | Fluorescein | ATP binding cassette subfamily C member 2 | Rattus norvegicus |
| 8 | CONCLUSIONS: D-glucose at the mucosal side activates fluorescein secretion across rat jejunum by an apical MRP, most probably by isoform 2 (MRP2), which could have an impact on the intestinal absorption of MRP substrates. | Fluorescein | ATP binding cassette subfamily C member 2 | Rattus norvegicus |
| 9 | CONCLUSIONS: D-glucose at the mucosal side activates fluorescein secretion across rat jejunum by an apical MRP, most probably by isoform 2 (MRP2), which could have an impact on the intestinal absorption of MRP substrates. | Fluorescein | ATP binding cassette subfamily C member 2 | Rattus norvegicus |