Pub. Date : 2004 May
PMID : 15136366
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rofecoxib, a COX-2 inhibitor, lowers C-reactive protein and interleukin-6 levels in patients with acute coronary syndromes. | rofecoxib | interleukin 6 | Homo sapiens |
| 2 | AIM: To evaluate whether patients with ACS treated with rofecoxib, a COX-2 inhibitor, will have reduced CRP, IL-6, and soluble tumor necrotic factor receptor-1 (sTNF-R1) levels and improved endothelial function. | rofecoxib | interleukin 6 | Homo sapiens |
| 3 | IL-6 levels were significantly lower at 1 month (p < 0.02) in the rofecoxib group, but not at 3 months. | rofecoxib | interleukin 6 | Homo sapiens |
| 4 | CONCLUSION: Patients recovering from ACS had lower levels of CRP and IL-6 at 1 month and lower CRP levels at 3 months when treated with rofecoxib plus aspirin. | rofecoxib | interleukin 6 | Homo sapiens |