Title : Mapping of the insulin-like growth factor II binding site of the Type I insulin-like growth factor receptor by alanine scanning mutagenesis.

Pub. Date : 2004 May 7

PMID : 15135045






2 Functional Relationships(s)
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1 Mapping of the insulin-like growth factor II binding site of the Type I insulin-like growth factor receptor by alanine scanning mutagenesis. Alanine insulin like growth factor 2 Homo sapiens
2 To characterize the molecular basis of the receptor"s ligand binding properties, we have examined the effects of alanine mutations of residues in the ligand binding site of the receptor on its affinity for IGF-II. Alanine insulin like growth factor 2 Homo sapiens