Title : The inhibitory effects of herbal components on CYP2C9 and CYP3A4 catalytic activities in human liver microsomes.

Pub. Date : 2004 May-Jun

PMID : 15133536






2 Functional Relationships(s)
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1 Ginsenoside Rd also had significant inhibitory potency on both CYP2C9- and CYP3A4-mediated index reactions with IC(50) values of 105 and 62 micromol/L, respectively. Ginsenosides cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 Our findings suggest that quercetin and ginsenoside Rd have the potential to interact with conventional medicines that are metabolized by CYP2C9 and CYP3A4 in vivo. Ginsenosides cytochrome P450 family 3 subfamily A member 4 Homo sapiens