Pub. Date : 2004 Jul 9
PMID : 15133037
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In response to epidermal growth factor (EGF), SHP-2 associates via its SH2 domains with tyrosyl-phosphorylated MVP. | cyclo(tyrosyl-tyrosyl) | protein tyrosine phosphatase non-receptor type 11 | Homo sapiens |
| 2 | MVP also interacts with the activated form of the extracellular-regulated kinases (Erks) in response to EGF and a constitutive complex between tyrosyl-phosphorylated MVP, SHP-2, and the Erks was detected in MCF-7 breast cancer cells. | cyclo(tyrosyl-tyrosyl) | protein tyrosine phosphatase non-receptor type 11 | Homo sapiens |
| 3 | The regulation of MVP tyrosyl phosphorylation by SHP-2 may play an important role in cell survival signaling. | cyclo(tyrosyl-tyrosyl) | protein tyrosine phosphatase non-receptor type 11 | Homo sapiens |