Title : Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand breaks in mitotic cells.

Pub. Date : 2004 Apr

PMID : 15126391






1 Functional Relationships(s)
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1 Although the role of the nuclease activity has been questioned in previous studies, the comparative data presented here suggest that the nuclease function of Mre11 is required for RMX-mediated recombinational repair and telomere stabilization in mitotic cells. 3-Chloro-4-(dichloromethyl)-2(5H)-furanone MRX complex nuclease subunit Saccharomyces cerevisiae S288C