| Protein Name | MRX complex nuclease subunit |
|---|---|
| Organism | Saccharomyces cerevisiae S288C |
| Gene ID | 855264 |
| Gene Symbol | MRE11 |
| UniProt | P32829 (MRE11_YEAST) |
| Relationships |
Total Number of functionally related compound(s) :
35
Total Number of Articles : 57 |
Description |
MRX complex nuclease subunit |
| Gene Summary |
Enables DNA binding activity; molecular adaptor activity; and nuclease activity. Contributes to AMP kinase activity. Involved in DNA metabolic process; ascospore formation; and regulation of transcription by RNA polymerase II. Located in nucleus. Part of Mre11 complex. Used to study breast cancer; intestinal cancer; liver cancer; ovarian cancer; and skin cancer. Human ortholog(s) of this gene implicated in several diseases, including Lynch syndrome; ataxia-telangiectasia-like disorder-1; endometrial cancer; gastrointestinal system cancer (multiple); and urinary bladder cancer. Orthologous to human MRE11 (MRE11 homolog, double strand break repair nuclease). [provided by Alliance of Genome Resources, Jun 2025] |
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