Title : Expression, up-regulation, and transport activity of the multidrug-resistance protein Abcg2 at the mouse blood-brain barrier.

Pub. Date : 2004 May 1

PMID : 15126373






1 Functional Relationships(s)
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1 Lastly, the defective P-gp in the mutant mdr1a(-/-) mice was associated with increased abcg2 mRNA at the BBB and a greater export of prazosin and mitoxantrone from the brain, as measured in the P-gp-deficient mice versus the wild-type mice. Prazosin ATP-binding cassette, sub-family B (MDR/TAP), member 1A Mus musculus