Title : Increase of cyclooxygenase-2 expression by interleukin 15 in rheumatoid synoviocytes.

Pub. Date : 2004 May

PMID : 15124245






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The increase of COX-2 by IL-15 is PGE2-dependent because exogenous PGE2 reversed the suppressive effect of NS-398, a selective COX-2 inhibitor, on COX-2 mRNA and protein expression. Dinoprostone interleukin 15 Homo sapiens
2 The increase of COX-2 by IL-15 is PGE2-dependent because exogenous PGE2 reversed the suppressive effect of NS-398, a selective COX-2 inhibitor, on COX-2 mRNA and protein expression. Dinoprostone interleukin 15 Homo sapiens
3 CONCLUSION: This study confirms the effect of IL-15 on upregulation of COX-2 in a PGE2-dependent manner. Dinoprostone interleukin 15 Homo sapiens