Title : NHERF2 increases platelet-derived growth factor-induced proliferation through PI-3-kinase/Akt-, ERK-, and Src family kinase-dependent pathway.

Pub. Date : 2004 Jul

PMID : 15115658






1 Functional Relationships(s)
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1 Pretreatment with PP2, a specific inhibitor of Src family tyrosine kinase, completely blocked the NHERF2-dependent increase of the phosphorylation of ERK and Akt, suggesting that NHERF2 up-regulates Erk phosphorylation through a Src family kinase-dependent pathway. pp2 AKT serine/threonine kinase 1 Rattus norvegicus