Title : Contribution of glutamine synthetase to ammonia-induced apoptosis in gastric mucosal cells.

Pub. Date : 2004

PMID : 15114044






1 Functional Relationships(s)
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1 BACKGROUND/AIMS: Glutamine synthetase is a key enzyme necessary for ammonia detoxification in the brain, but excessive activation of this enzyme can be cytotoxic to neural cells as a consequence of excessive consumption of ATP and glutamate. Glutamic Acid glutamate-ammonia ligase Rattus norvegicus