Title : MHC-peptide binding is assisted by bound water molecules.

Pub. Date : 2004 Apr 23

PMID : 15066441






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 These water molecules in the interface perform definite "tasks" contributing to the binding energy: hydrogen bond bridges between MHC and peptide and filling empty spaces in the groove which enhance affinity without contributing to epitope specificity. Hydrogen major histocompatibility complex, class I, C Homo sapiens