Title : BCR/ABL translocates to the nucleus and disrupts an ATR-dependent intra-S phase checkpoint.

Pub. Date : 2004 Mar

PMID : 15050919






1 Functional Relationships(s)
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1 Furthermore, BCR/ABL increases DNA double-strand damage after etoposide treatment and leads to a defect in an intra-S phase checkpoint, causing a radioresistant DNA synthesis (RDS) phenotype. Etoposide ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens