Title : Fos expression in intrastriatal striatal grafts: regulation by host dopaminergic afferents.

Pub. Date : 1992 Jun 26

PMID : 1504828






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Amphetamine (5 mg/kg; 2 h) induced Fos-like immunoreactivity in clusters of cells located mainly within the DARPP-32-positive areas within the transplants, i.e. within the striatum-like graft compartment which is preferentially innervated by the host DA afferents. Amphetamine Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 In intrastriatal grafts of fetal neocortical tissue, which were studied for comparison, the amphetamine- and apomorphine-induced effects on Fos expression were much smaller and similar to that seen in the DARPP-32-negative, non-striatal compartment within the striatal grafts. Amphetamine Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus