Title : p38 MAPK activation selectively induces cell death in K-ras-mutated human colon cancer cells through regulation of vitamin D receptor.

Pub. Date : 2004 May 21

PMID : 15037631






1 Functional Relationships(s)
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1 p38 activation by both adenovirus-mediated gene delivery of constitutively active p38 activator MKK6 and by arsenite selectively induces cell death in K-ras-activated human colon cancer HCT116 cells but not in the K-ras-disrupted HCT116-derived sublines. arsenite mitogen-activated protein kinase 14 Homo sapiens