Title : Cyclosporin-A inhibits inducible nitric oxide synthase activity and expression after spinal cord injury in rats.

Pub. Date : 2004 Feb 26

PMID : 15036611






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Cyclosporin-A (CsA), an immunosupressive agent, may be used to inhibit the activity of iNOS and perhaps to protect against neural tissue destruction. Cyclosporine nitric oxide synthase 2 Rattus norvegicus
2 Cyclosporin-A (CsA), an immunosupressive agent, may be used to inhibit the activity of iNOS and perhaps to protect against neural tissue destruction. Cyclosporine nitric oxide synthase 2 Rattus norvegicus
3 Results showed an increase in the activity of iNOS at 72 h after the SCI, inhibited by CsA (2.5 mg/kg) administered 12 h after trauma. Cyclosporine nitric oxide synthase 2 Rattus norvegicus
4 iNOS Western blot assay showed an increase in the expression of iNOS after trauma, also antagonized by CsA administration. Cyclosporine nitric oxide synthase 2 Rattus norvegicus
5 iNOS Western blot assay showed an increase in the expression of iNOS after trauma, also antagonized by CsA administration. Cyclosporine nitric oxide synthase 2 Rattus norvegicus