Pub. Date : 2004 Mar 30
PMID : 15033564
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We have now demonstrated that minus strand synthesis is strongly repressed upon the binding of eEF1A.GTP to the valylated viral RNA. | Guanosine Triphosphate | eukaryotic translation elongation factor 1 alpha 1 | Homo sapiens |
| 2 | Higher eEF1A.GTP levels were needed to repress minus strand synthesis templated by valyl-EMV TLS RNA, which binds eEF1A.GTP with lower affinity than does valyl-TYMV RNA. | Guanosine Triphosphate | eukaryotic translation elongation factor 1 alpha 1 | Homo sapiens |
| 3 | Higher eEF1A.GTP levels were needed to repress minus strand synthesis templated by valyl-EMV TLS RNA, which binds eEF1A.GTP with lower affinity than does valyl-TYMV RNA. | Guanosine Triphosphate | eukaryotic translation elongation factor 1 alpha 1 | Homo sapiens |
| 4 | Higher eEF1A.GTP levels were needed to repress minus strand synthesis templated by valyl-EMV TLS RNA, which binds eEF1A.GTP with lower affinity than does valyl-TYMV RNA. | Guanosine Triphosphate | eukaryotic translation elongation factor 1 alpha 1 | Homo sapiens |
| 5 | Higher eEF1A.GTP levels were needed to repress minus strand synthesis templated by valyl-EMV TLS RNA, which binds eEF1A.GTP with lower affinity than does valyl-TYMV RNA. | Guanosine Triphosphate | eukaryotic translation elongation factor 1 alpha 1 | Homo sapiens |
| 6 | Repression by eEF1A.GTP was also observed with a methionylated variant of TYMV RNA and with aminoacylated tRNAHis, tRNAAla, and tRNAPhe transcripts. | Guanosine Triphosphate | eukaryotic translation elongation factor 1 alpha 1 | Homo sapiens |
| 7 | It is proposed that minus strand repression by eEF1A.GTP binding occurs early during infection to help coordinate the competing translation and replication functions of the genomic RNA. | Guanosine Triphosphate | eukaryotic translation elongation factor 1 alpha 1 | Homo sapiens |