Title : Integrating three views of Arf1 activation dynamics.

Pub. Date : 2004 Apr 2

PMID : 15033364






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 It is suggested that Sec7d groove closure upon docking of the two molecules may permit extraction of switch 1 from Arf1-GDP and prepare the complex for movement of the interswitch, which is central to the membrane-linked exchange activity. Guanosine Diphosphate ADP ribosylation factor 1 Homo sapiens
2 Large-scale collective movements in the Arf1-Sec7d complex appear to participate in the insertion of the Sec7d Glu finger into the GDP binding site to promote actual nucleotide release. Guanosine Diphosphate ADP ribosylation factor 1 Homo sapiens