Pub. Date : 2004 Apr
PMID : 15026282
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | DMH injections significantly elevated both the activities of beta-glucuronidase (distal colon, distal intestine, liver and colon contents) and mucinase (colon and fecal contents) as compared to the control rats. | 1,2-Dimethylhydrazine | glucuronidase, beta | Rattus norvegicus |
| 2 | Coconut cake supplementation to DMH-treated rats significantly decreased the incidence and number of tumors as well as the activity of beta-glucuronidase and mucinase. | 1,2-Dimethylhydrazine | glucuronidase, beta | Rattus norvegicus |
| 3 | CONCLUSIONS: Coconut cake has a protective effect against DMH induced colon cancer by virtue of its ability to lower the activities of the microbial enzymes beta-glucuronidase and mucinase. | 1,2-Dimethylhydrazine | glucuronidase, beta | Rattus norvegicus |