Protein Name glucuronidase, beta
Organism Rattus norvegicus
Gene ID 24434
Gene Symbol

Gusb

UniProt P06760 (BGLR_RAT)
Relationships Total Number of functionally related compound(s) : 466
Total Number of Articles : 429
Description

glucuronidase, beta

Gene Summary

Enables beta-glucuronidase activity and carbohydrate binding activity. Predicted to be involved in chondroitin sulfate proteoglycan catabolic process; heparan sulfate proteoglycan catabolic process; and hyaluronan catabolic process. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be active in extracellular space and lysosomal lumen. Biomarker of mucopolysaccharidosis and peritonitis. Human ortholog(s) of this gene implicated in mucopolysaccharidosis type VII. Orthologous to human GUSB (glucuronidase beta). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • beta-glucuronidase
  • Ac2-223
  • Gus-s
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Properties