Pub. Date : 2004 Mar 1
PMID : 15014043
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells. | rangtp | regulator of chromosome condensation 1 | Homo sapiens |
| 2 | This phosphorylation is necessary for RCC1 to generate RanGTP on mitotic chromosomes in mammalian cells, which in turn is required for spindle assembly and chromosome segregation. | rangtp | regulator of chromosome condensation 1 | Homo sapiens |
| 3 | Moreover, phosphorylation of the NLS of RCC1 is required to prevent the binding of importin alpha and beta to RCC1, thereby allowing RCC1 to couple RanGTP production to chromosome binding. | rangtp | regulator of chromosome condensation 1 | Homo sapiens |
| 4 | Moreover, phosphorylation of the NLS of RCC1 is required to prevent the binding of importin alpha and beta to RCC1, thereby allowing RCC1 to couple RanGTP production to chromosome binding. | rangtp | regulator of chromosome condensation 1 | Homo sapiens |
| 5 | Moreover, phosphorylation of the NLS of RCC1 is required to prevent the binding of importin alpha and beta to RCC1, thereby allowing RCC1 to couple RanGTP production to chromosome binding. | rangtp | regulator of chromosome condensation 1 | Homo sapiens |