Title : Benzimidazolone p38 inhibitors.

Pub. Date : 2004 Feb 23

PMID : 15012994






3 Functional Relationships(s)
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Protein Name
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1 The p38 alpha SAR is consistent with a mode of binding wherein the benzimidazolone carbonyl serves as the H-bond acceptor to Met109 of p38 alpha in a manner analogous to the pyridine nitrogen of prototypical pyridylimidazole p38 inhibitors. pyridine mitogen-activated protein kinase 14 Homo sapiens
2 The p38 alpha SAR is consistent with a mode of binding wherein the benzimidazolone carbonyl serves as the H-bond acceptor to Met109 of p38 alpha in a manner analogous to the pyridine nitrogen of prototypical pyridylimidazole p38 inhibitors. pyridine mitogen-activated protein kinase 14 Homo sapiens
3 The p38 alpha SAR is consistent with a mode of binding wherein the benzimidazolone carbonyl serves as the H-bond acceptor to Met109 of p38 alpha in a manner analogous to the pyridine nitrogen of prototypical pyridylimidazole p38 inhibitors. pyridine mitogen-activated protein kinase 14 Homo sapiens