Pub. Date : 2004 May 7
PMID : 14988393
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ZVAD, the pancaspase inhibitor, and Bcl-2 annulled the effect of Act D on SK1, demonstrating a role for cysteine proteases downstream of Bcl-2 in the down-regulation of SK1. | benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone | BCL2 apoptosis regulator | Homo sapiens |
| 2 | Inhibition of cathepsin B, a lysosomal protease, produced a significant reversal of SK1 decline by Act D, suggesting that a multitude of ZVAD-sensitive cysteine proteases downstream of Bcl-2 mediated the SK1 decrease. | benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone | BCL2 apoptosis regulator | Homo sapiens |