Title : Oxygen stress effects on proliferation rates and heat shock proteins in lymphocytes.

Pub. Date : 2004 Feb

PMID : 14960044






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Although an increased expression of HSP72/73 was observed in each group 6 h after oxygen stress, only 100 micromol x L(-1) H2O2-treated cells remained at a high expression level after 24 h. CONCLUSION: It is likely that when cells encounter oxygen stress, an increased expression of HSP72/73 and subsequent repair of damaged proteins cause the retardation of cell cycle progression and prevent damaged cells from entering the S phase. Hydrogen Peroxide heat shock protein family A (Hsp70) member 1A Homo sapiens
2 Although an increased expression of HSP72/73 was observed in each group 6 h after oxygen stress, only 100 micromol x L(-1) H2O2-treated cells remained at a high expression level after 24 h. CONCLUSION: It is likely that when cells encounter oxygen stress, an increased expression of HSP72/73 and subsequent repair of damaged proteins cause the retardation of cell cycle progression and prevent damaged cells from entering the S phase. Hydrogen Peroxide heat shock protein family A (Hsp70) member 1A Homo sapiens
3 From our results of the HSP72/73 experiment, the threshold that determines the fate of the lymphocytes may be around 100 micromol x L(-1) H2O2. Hydrogen Peroxide heat shock protein family A (Hsp70) member 1A Homo sapiens