Title : The effect of insulin and exercise on c-Cbl protein abundance and phosphorylation in insulin-resistant skeletal muscle in lean and obese Zucker rats.

Pub. Date : 2004 Mar

PMID : 14730380






1 Functional Relationships(s)
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1 AIMS/HYPOTHESIS: Recruitment of the protein c-Cbl to the insulin receptor (IR) and its tyrosine phosphorylation via a pathway that is independent from phosphatidylinositol 3"-kinase is necessary for insulin-stimulated GLUT4 translocation in 3T3-L1 adipocytes. Tyrosine insulin receptor Rattus norvegicus