Title : Treosulfan-induced apoptosis in acute myeloid leukemia cells is accompanied by translocation of protein kinase C delta and enhanced by bryostatin-1.

Pub. Date : 2004 Jan

PMID : 14725904






3 Functional Relationships(s)
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1 Treosulfan-induced apoptosis in acute myeloid leukemia cells is accompanied by translocation of protein kinase C delta and enhanced by bryostatin-1. treosulfan protein kinase C delta Homo sapiens
2 Immunoblots revealed membrane translocation of PKC-delta, indicating activation of this enzyme upon treosulfan exposure. treosulfan protein kinase C delta Homo sapiens
3 Furthermore, the proapoptotic effect of treosulfan is mediated at least in part by activation of PKC isoforms and can be augmented by coincubation with bryostatin-1. treosulfan protein kinase C delta Homo sapiens