Title : [The reverse effect on drug-resistance against tyrosine kinase inhibitor STI571 in mdr1 and bcr-abl positive leukemic cells].

Pub. Date : 2003 Dec

PMID : 14706143






1 Functional Relationships(s)
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1 To explore the possibility of leukemia cell line of both bcr-abl and mdr-1 positive were cross-resistant to tyrosine kinase inhibitor STI571 and its reversal way, the inhibitory effect of STI571 on K562-n/VCR cells was detected with MTT method and reverse effects of CsA, TAM, IFN-alpha and CsA cominated with IFN-alpha were observed. monooxyethylene trimethylolpropane tristearate ATP binding cassette subfamily B member 1 Homo sapiens