Title : [To inhibit ERK for enhancing chemotherapy sensitivity of drug-resistance cell lines of leukemia and ovarian carcinoma].

Pub. Date : 2003 Dec

PMID : 14706142






1 Functional Relationships(s)
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1 The results showed that the specific inhibitor PD98059 of ERK kinase 1 (MEK(1)) enhanced the sensitivity of HL-60/E6 leukemia cell lines to harringtonine (HRT) or COC1/DDP ovarian carcinoma cell lines to cis-dichlorodiamine platinum (DDP). harringtonin mitogen-activated protein kinase 1 Homo sapiens