Title : Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases.

Pub. Date : 2004 Mar 26

PMID : 14701854






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1 Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. epigallocatechin gallate epidermal growth factor receptor Homo sapiens
2 In the present study, we investigated the effects of epigallocatechin-3-gallate (EGCG), a bioactive green tea polyphenol, on EGFR signaling in cervical cells. epigallocatechin gallate epidermal growth factor receptor Homo sapiens
3 In the present study, we investigated the effects of epigallocatechin-3-gallate (EGCG), a bioactive green tea polyphenol, on EGFR signaling in cervical cells. epigallocatechin gallate epidermal growth factor receptor Homo sapiens
4 EGCG inhibits epidermal growth factor-dependent activation of EGFR, and EGFR-dependent activation of the mitogen-activated protein kinases ERK1/2. epigallocatechin gallate epidermal growth factor receptor Homo sapiens
5 EGCG also inhibits EGFR-dependent AKT activity. epigallocatechin gallate epidermal growth factor receptor Homo sapiens