Title : Design and synthesis of hydroxyethylene-based peptidomimetic inhibitors of human beta-secretase.

Pub. Date : 2004 Jan 1

PMID : 14695829






1 Functional Relationships(s)
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Protein Name
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1 Compound 20 with the N-terminal isophthalamide proved to be the most potent HE inhibitor (IC(50) = 30 nM) toward BACE. Isophthalamide beta-secretase 1 Homo sapiens