Title : [Comparison of the toxic effect of methamidophos and acephate on acetylcholinesterase].

Pub. Date : 2002 Dec

PMID : 14694584






3 Functional Relationships(s)
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1 [Comparison of the toxic effect of methamidophos and acephate on acetylcholinesterase]. acephate acetylcholinesterase Rattus norvegicus
2 When rats being administrated with acephate, there was 31.68% of inhibition on the brain stem, but no significant inhibition in other brain region was noticed, while methamidophos had a strong inhibitory effect on the activity of AChE in all brain regions, especially the cerebellum and brain-stem(71.51% and 61.85% respectively). acephate acetylcholinesterase Rattus norvegicus
3 CONCLUSION: Acephate and methamidophos could directly inhibit the AChE activities in vitro, but the inhibition degree was different. acephate acetylcholinesterase Rattus norvegicus