Title : Human uncoupling protein-3 and obesity: an update.

Pub. Date : 2003 Dec

PMID : 14694206






9 Functional Relationships(s)
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Protein Name
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1 The observation that fatty acid levels significantly affect UCP3 expression has given UCP3 a position in fatty acid handling and/or oxidation. Fatty Acids uncoupling protein 3 (mitochondrial, proton carrier) Mus musculus
2 The observation that fatty acid levels significantly affect UCP3 expression has given UCP3 a position in fatty acid handling and/or oxidation. Fatty Acids uncoupling protein 3 (mitochondrial, proton carrier) Mus musculus
3 The observation that fatty acid levels significantly affect UCP3 expression has given UCP3 a position in fatty acid handling and/or oxidation. Fatty Acids uncoupling protein 3 (mitochondrial, proton carrier) Mus musculus
4 The observation that fatty acid levels significantly affect UCP3 expression has given UCP3 a position in fatty acid handling and/or oxidation. Fatty Acids uncoupling protein 3 (mitochondrial, proton carrier) Mus musculus
5 Emerging data indicate that the primary physiological role of UCP3 may be the mitochondrial handling of fatty acids rather than the regulation of energy expenditure through thermogenesis. Fatty Acids uncoupling protein 3 (mitochondrial, proton carrier) Mus musculus
6 It has been proposed that UCP3 functions to export fatty acid anions away from the mitochondrial matrix. Fatty Acids uncoupling protein 3 (mitochondrial, proton carrier) Mus musculus
7 In doing so, fatty acids are exchanged with protons, explaining the uncoupling activity of UCP3. Fatty Acids uncoupling protein 3 (mitochondrial, proton carrier) Mus musculus
8 Regardless of the origin of the fatty acid anions, this putative function of UCP3 might be of great importance in protecting mitochondria against fatty acid accumulation and may help to maintain muscular fat oxidative capacity. Fatty Acids uncoupling protein 3 (mitochondrial, proton carrier) Mus musculus
9 Regardless of the origin of the fatty acid anions, this putative function of UCP3 might be of great importance in protecting mitochondria against fatty acid accumulation and may help to maintain muscular fat oxidative capacity. Fatty Acids uncoupling protein 3 (mitochondrial, proton carrier) Mus musculus